The genomics evolution
نویسندگان
چکیده
منابع مشابه
The evolution of comparative genomics
The field of comparative genomics arose hand-in-hand with the ability to generate genomic sequence data. The first computer algorithms to compare amino acid sequences were developed over forty years ago (Fitch 1966; Needleman and Wunsch 1970)and improved upon as nucleic acid sequencing advanced (Sanger et al. 1977) with the application of improved statistical methods to the growing database of ...
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A major goal of evolutionary biology is to understand the genetics of adaptation. What is the relationship between adaptive phenotypic changes and changes in the genome? Are adaptive phenotypic changes caused by alterations at many loci of small effect, at a few loci of large effect, or some combination of the two? What are the effects on adaptive evolution of complexities such as the multiple ...
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1 Harvard T. H. Chan School of Public Health. Department of Environmental Health Molecular and Integrative Physiology Program. Corresponding author: Alan T. Branco Email: [email protected] Suggested citation: Branco AT. The evolution of genetics to genomics. J Hum Growth Dev. 26(1): 28-32. Doi: http://dx.doi.org/10.7322/jhgd.113710 Manuscript submitted: Oct 3
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ژورنال
عنوان ژورنال: Nature Reviews Drug Discovery
سال: 2004
ISSN: 1474-1776,1474-1784
DOI: 10.1038/nrd1454